Preventing the Overlapping Epidemics of HIV & Genital Herpes

Preventing the Overlapping Epidemics of HIV & Genital Herpes
Betsy C Herold, M.D. Albert Einstein College of Medicine, Children's Hospital at Montefiore
HIV Center for Clinical and Behavioral Studies, Columbia University, New York, NY

Table of Contents

Introduction

0:00:00

Epidemiology of HIV

0:00:39

Risk of Acquisition/Transmission

0:01:57

Strategies for HIV Prevention

0:06:59

Topical Prep

0:12:07

Clinical trials: From Failure to Success

0:13:36

From the Bedside to the Bench & Back Again

CVL as Surrogate of Pharmacodynamics:

0:27:07

Interference Traslates to Protection in Murine HSV Model

0:30:06

What happens to drug PK/PD following sex?

0:31:08

Loss in Antiviral Activity (PD) and Drug Recovered (PK) in postcoital CVL

0:32:32

Loss in Antiviral Activity (PD) and Drug Recovered (PK) in postcoital CVL

0:35:19

Implicatoins: Sex & Semen

0:35:31

Reconsidering Safety: Standard safety measures

0:38:13

Dual-chamber model- Safety

0:40:55

Confocal images indicate disruption results in increased HSV transmission

0:42:24

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In this presentation, Betsy Herold, M.D. speaks about preventing the overlapping epidemics of HIV & genital herpes.

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Jun 02, 2011	864	VA:06:02:6176:2011

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