ShK peptide treatment of Lewis rats with adoptive experimental autoimmune encephalomyelitis following the adoptive transfer of m
Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, Cahalan MD, Chandy KG, Béraud E.
(1) Laboratoire d'Immunologie, Faculté de Médecine, 13385 Marseille, France; (2) Department of Physiology and Biophysics, University of California, Irvine, CA 92697; (3) Bachem Bioscience, King of Prussia, PA 19406
Adoptive transfer of T cells specific for myelin basic protein (PAS cell line) into healthy Lewis rats induces experimental autoimmune encephalomyelitis (EAE), a disease that resembles multiple sclerosis in humans.
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Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, Cahalan MD, Chandy KG, Béraud E. Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. Proc Natl Acad Sci U S A. 2001, 98:13942-7
Beeton C, Barbaria J, Giraud P, Devaux J, Benoliel AM, Gola M, Sabatier JM, Bernard D, Crest M, Béraud E. Selective blocking of voltage-gated K+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation. J Immunol. 2001, 166:936-44.
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