Diabetic Ketoacidosis in Children

Arleta Rewers, Robert Slover
Department of Pediatrics and Barbara Davis Center for Childhood Diabetes, University of Colorado Health Science Center, Denver, Colorado
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The incidence of DKA increased significantly with age in girls but t...
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The Proportion of Children with Recurrent DKA , shown on this graph, ...
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Average cost of hospitalization of a diabetic patient doubles, if DKA...
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Patients met diagnostic criteria for cerebral edema 3.1 /-2.6 hours ...
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Some have suggested early and late peaks.
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Ketone bodies are produced in large amounts as a physiological metabo...
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The Abbott / MediSense device is known in the U.S. as Precision Xtra ...
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In a normal sate, after a meal, most of the energy is derived from gl...
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Post-prandial insulin facilitates glucose oxidation and lipogenesis, ...
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Insulin suppresses also the HMG CoA synthase and production of ketone...
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In DKA, lack of insulin and excess of counter-regulatory hormones, pr...
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Most validation studies have found a strong correlation between the b...
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Another standard way to look at this is the Bland-Altman plot analysi...
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Measurement of beta-OHB in blood, as expected, is a more sensitive ap...
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Four studies, summarized here, have looked at this issue. Each used a...
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Data from Prisco et al. elegantly illustrates this point. Among 118 c...
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In our recent paper, we found very good correlation between the bedsi...
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pH, bicarbonate, pCO2 were entered into separate time series analysis...
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In the majority of type 1 diabetic children, normalization of blood b...
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This is a typical profile of bedside beta-hydroxybutyrate throughout ...
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Neuro status: mental status, level of alertness, ability to arouse.
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This lecture provides an overview of diabetic ketoacidosis in children.
 
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Jan 30, 2010 732 VA:01:30:2478:2010
 
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